Events
-
2025/03/27 Correctseq
Precise and Efficient RNA Editing by Cleaving ADAR Inhibitor
Recently, a collaborative team led by Professor Chen Jia from the School of Life Science and Technology (SLST) at ShanghaiTech University and Professor Yang Li at Fudan University published a study titled “Specific and Efficient RNA A-to-I Editing through Cleavage of an ADAR Inhibitor”in Nature Biotechnology.
-
2025/03/27 Correctseq
An Efficient and Precise Mitochondrial Adenine Base Editor
Mitochondria, the “powerhouses” of cells, play a vital role in adenosine triphosphate (ATP) production. Mitochondria possess their own independent DNA, termed mitochondrial DNA (mtDNA), which encodes
-
2023/11/24 Correctseq
CorrectSequence Therapeutics (Correctseq), a biotechnology company using innovative base editing technology to help people with severe disease, today announced that the company and the research teams from ShanghaiTech University, Wuhan University, Fudan University and Children's Hospital of Fudan University published an article entitled “Base editing of the HBG promoter induces potent fetal hemoglobin expression with no detectable off-target mutations in human HSCs” in Cell Stem Cell on November 20th, 2023, reporting a novel base editing strategy for treating β-hemoglobinopathies with transformer base editor (tBE).
-
2023/10/12 Correctseq
Nature Reviews Molecular Cell Biology：Base editing of organellar DNA with programmable deaminases
Recently, Prof. Jia Chen from ShanghaiTech University and Prof. Jin-Soo Kim from National University of Singapore published a review entitled Base editing of organellar DNA with programmable deaminases in Nature Reviews Molecular Cell Biology.
-
2023/10/06 Correctseq
Nature Protocols：Design and Application of the transformer Base Editor in Mammalian Cells and Mice
Prof. Jia Chen's research team and Prof. Jianfeng Li's research team at ShanghaiTech University, and Prof. Li Yang's research team at the Center for Molecular Medicine, Children’s Hospital, Fudan University jointly published a protocol paper in Nature Protocols, entitled Design and application of the transformer base editor in mammalian cells and mice. The paper describes the working principle, design scheme, and in vivo editing by the tBE.
-
2022/12/30 Correctseq
transformer Base Editor of Correctseq Wins the 19th People's Ingenuity Award
The 2022 People's Financial Summit Forum, hosted by www.people.cn online, was held in Beijing on Dec 29. The winners of the 19th People's Ingenuity Award were officially released at the forum. transformer Base Editor (tBE), which is developed by the scientific co-founders of CorrectSequence Therapeutics (Correctseq), won the Ingenuity Award for its higher editing efficiency and better safety in the whole genome and whole transcriptome, and promising to completely cure single base genetic diseases. Correctseq also became the only biotech pharmaceutical company to receive this award.
-
2022/08/05 Correctseq
On Aug 2-4, 2022, National Medical Products Administration Institute of Executive Development hold Drug Researcher Conference online. Dr Lijie Wang, head of CorrectSequence Therapeutics (Correctseq) Gene Editing Platform, was invited to attend the conference and made a speech on the topic of “the Latest Advances and Clinical Applications of Gene Editing”. (Online Live| Drug Researcher Conference( Topic: Biologics Registration Regulations and Applications)